| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-07-03 |
| タイトル |
|
|
タイトル |
Incomplete maternal transmission of mitochondrial DNA in Drosophila |
| タイトル |
|
|
タイトル |
Incomplete maternal transmission of mitochondrial DNA in Drosophila |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
metadata only access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 著者 |
KONDO, Rumi
SATTA, Yoko
MATSUURA, Etsuko T
ISHIKAWA, H
TAKAHATA, Naoyuki
CHIGUSA, Sadao I
|
| 著者別名 |
尚之, 高畑
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The possibility of incomplete maternal transmission of mitochondrial DNA (mtDNA) in Drosophila, previously suggested by the presence of heteroplasmy, was examined by intra- and interspecific backcrosses of Drosophila simulans and its closest relative, Drosophila mauritiana. mtDNAs of offspring in these crosses were characterized by Southern hybridization with two alpha-32P-labeled probes that are specific to paternal mtDNAs. This method could detect as little as 0.03% paternal mtDNA, if present, in a sample. Among 331 lines that had been backcrossed for ten generations, four lines from the interspecific cross D. simulans (female) x D. mauritiana (male) showed clear evidence for paternal leakage of mtDNA. In three of these the maternal type was completely replaced while the fourth was heteroplasmic. Since in this experiment the total number of fertilization is known to be 331 x 10 = 3310, the proportion of paternal mtDNA per fertilization was estimated as about 0.1%. The mechanisms and evolutionary significance for paternal leakage are discussed in light of this finding. |
| 書誌情報 |
Genetics
en : Genetics
巻 126,
号 3,
p. 657-663,
発行日 1990
|
| 出版者 |
|
|
出版者 |
The Genetics Society of America |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
00166731 |
| PubMed番号 |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
2249764 |
| 権利 |
|
|
権利情報 |
© 1990 by The Genetics Society of America |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
