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Estimating evolutionary distance from restriction maps of mitochondrial DNA with arbitrary G+C content
https://ir.soken.ac.jp/records/3741
https://ir.soken.ac.jp/records/37414c3dba2b-7085-44bf-9e8d-20fcbbc206f1
| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||
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| 公開日 | 2013-07-04 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Estimating evolutionary distance from restriction maps of mitochondrial DNA with arbitrary G+C content | |||||||||||
| タイトル | ||||||||||||
| タイトル | Estimating evolutionary distance from restriction maps of mitochondrial DNA with arbitrary G+C content | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| アクセス権 | ||||||||||||
| アクセス権 | metadata only access | |||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||||||||
| 著者 |
TATENO, Yoshio
× TATENO, Yoshio
× AOKI, Kenichi
× TAKAHATA, Naoyuki
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| 著者別名 |
尚之, 高畑
× 尚之, 高畑
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | We develop a mathematical model for estimating evolutionary distance from restriction enzyme maps, which incorporates non-uniformity of the rate of base substitution into the theory and allows for an arbitrary G+C content at equilibrium. When the G+C content differs significantly from 1/2, the traditional model of base changes can introduce a systematic bias which depends upon the base composition of the restriction site. In addition, the accuracy of estimated evolutionary distance depends heavily upon the choice of restriction enzyme in that the expected number of sites is also affected. Monte Carlo experiments are conducted to check the validity of the present theoretical treatment and from which we draw several cautionary notes on estimation. An application is made to the available data on restriction enzyme maps of human mitochondrial DNA where the G+C content is approximately 1/3. | |||||||||||
| 書誌情報 |
Journal of Molecular Evolution en : Journal of Molecular Evolution 巻 18, 号 1, p. 1-8, 発行日 1981-01 |
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| 出版者 | ||||||||||||
| 出版者 | SpringerLink | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 00222844 | |||||||||||
| PubMed番号 | ||||||||||||
| 識別子タイプ | PMID | |||||||||||
| 関連識別子 | 6278152 | |||||||||||
| DOI | ||||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | http://doi.org/10.1007/BF01733204 | |||||||||||
| 関連名称 | 10.1007/BF01733204 | |||||||||||
| 権利 | ||||||||||||
| 権利情報 | SpringerLink(The original publication is available at www.springerlink.com) | |||||||||||
