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Oxidative DNA damage induced by 364-nm UVA laser in yeast cells
https://ir.soken.ac.jp/records/4525
https://ir.soken.ac.jp/records/4525b80962e3-431b-46ae-88fa-e9c26bfdaf9e
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-05-16 | |||||
タイトル | ||||||
タイトル | Oxidative DNA damage induced by 364-nm UVA laser in yeast cells | |||||
タイトル | ||||||
タイトル | Oxidative DNA damage induced by 364-nm UVA laser in yeast cells | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
NEGISHI, Kazuo
× NEGISHI, Kazuo× WATANABE, Masakatsu× et, al. |
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著者別名 |
渡辺, 正勝
× 渡辺, 正勝 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The mechanisms of the toxic effects of UVA (320-400nm) irradiation remain unclear. The actions of monochromatic longer wavelength UVA, in particular, have been difficult to analyze because of a lack of a powerful light source; however, a UVA laser that can be used for biological studies was recently developed. In the current studies, we examined the effects of 364-nm irradiation on yeast cells using a potent UVA laser. We found that, when irradiated under aerobic conditions, yeast cells lacking Ogg1 glycosylase were more sensitive than those with Ogg1. The ability of the 364-nm light to kill the yeast cells was almost eliminated by purging with argon gas. The mutagenic effects of the UVA irradiation did not appear to be enhanced by a lack of Ogg1. These results indicate the killing of yeast cells by 364-nm UVA may be dependent on oxidation and may involve DNA lesions that can be repaired by Ogg1. | |||||
書誌情報 |
環境変異原研究 en : Genes and environment : the official journal of the Japanese Environmental Mutagen Society 巻 28, 号 2, p. 74-76, 発行日 2006 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18807046 | |||||
書誌レコードID (NCID) | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA1212552X | |||||
論文ID(NAID) | ||||||
識別子タイプ | NAID | |||||
関連識別子 | 110004749522 | |||||
権利 | ||||||
権利情報 | © The Japanese Environmental Mutagen Society | |||||
関連サイト | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://ci.nii.ac.jp/naid/110004749522/ | |||||
関連名称 | CiNii 論文PDF - オープンアクセス |