| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-08-02 |
| タイトル |
|
|
タイトル |
Early Duplication of a Single MHC IIB Locus Prior to the Passerine Radiations. |
| タイトル |
|
|
タイトル |
Early Duplication of a Single MHC IIB Locus Prior to the Passerine Radiations. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
EIMIS, John A
LEE, Sang-Im
TOWNSEND, Andrea K
JABLONSKI, Piotr
NISHIUMI, Isao
SATTA, Yoko
|
| 著者別名 |
EIMIS, John A
LEE, Sang-Im
TOWNSEND, Andrea K
JABLONSKI, Piotr
NISHIUMI, Isao
SATTA, Yoko
|
| 著者注記 |
|
|
|
Yoko, Satta：The Graduate University for Advanced Studies, Department of Evolutionary Studies of Biosystems *(Professor) |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
A key characteristic of MHC genes is the persistence of allelic lineages over macroevolutionary periods, often through multiple speciation events. This phenomenon, known as trans-species polymorphism (TSP), is well documented in several major taxonomic groups, but has less frequently been observed in birds. The order Passeriformes is arguably the most successful terrestrial vertebrate order in terms of diversity of species and ecological range, but the reasons for this success remain unclear. Passerines exhibit the most highly duplicated MHC genes of any major vertebrate taxonomic group, which may generate increased immune response relative to other avian orders with fewer MHC loci. Here, we describe phylogenetic patterns of the MHC IIB in the passerine family Corvidae. Our results indicate wide-spread TSP within this family, with at least four supported MHC IIB allelic lineages that predate speciation by many millions of years. Markov chain Monte Carlo simulations indicate that divergence of these lineages occurred near the time of the divergence of the Passeriformes and other avian orders. We suggest that the current MHC diversity observed in passerines is due in part to the multiple duplication of a single MHC locus, DAB1, early in passerine evolution and that subsequent duplications of these paralogues have contributed to the enormous success of this order by increasing their ability to recognize and mount immune responses to novel pathogens. |
| 書誌情報 |
PLoS ONE
en : PLoS ONE
巻 11,
号 9,
p. e0163456,
発行日 2016-09-22
|
| 雑誌情報 |
|
|
|
Publication Start Year : 2006 |
| 雑誌情報 |
|
|
|
Frequency : Monthly |
| 雑誌情報 |
|
|
|
A Peer-Reviewed, Open Access Journal, Electronic only |
| 出版者 |
|
|
出版者 |
Public Library of Science / San Francisco, CA |
| Online ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1932-6203 |
| PubMed番号 |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
27658204 |
| PMC番号 |
|
|
|
PMC5033386 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1371/journal.pone.0163456 |
|
|
関連名称 |
10.1371/journal.pone.0163456 ＜PLoS ONE Open Access Full Text＞ |
| 権利 |
|
|
権利情報 |
© 2016 Eimes et al. |
| 権利 |
|
|
権利情報 |
※ This is an open-access article distributed under the terms of the Creative Commons Attribution License. which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| 関連サイト |
|
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033386/ |
|
|
関連名称 |
Article ＜PMC FREE Full text＞ |
| 関連サイト |
|
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://www.ncbi.nlm.nih.gov/pmc/journals/440/ |
|
|
関連名称 |
Archive of PLoS ONE ＜PMC Journal List＞ |
| 関連サイト |
|
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
http://journals.plos.org/plosone/ |
|
|
関連名称 |
About PLoS ONE ＜Public Library of Science＞ |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
本文 / Article (2.9 MB)
.png)
