| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-07-19 |
| タイトル |
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タイトル |
The origin and evolution of fibromelanosis in domesticated chickens: Genomic comparison of Indonesian Cemani and Chinese Silkie breeds. |
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タイトル |
The origin and evolution of fibromelanosis in domesticated chickens: Genomic comparison of Indonesian Cemani and Chinese Silkie breeds. |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
DHARMAYANTHI, Anik Budhi
TERAI, Yohei
SULANDARI, Sri
ZEIN, M Syamsul Arifin
AKIYAMA, Toyoko
SATTA, Yoko
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| 著者別名 |
DHARMAYANTHI, Anik Budhi
TERAI, Yohei
SULANDARI, Sri
ZEIN, M Syamsul Arifin
AKIYAMA, Toyoko
SATTA, Yoko
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| 著者注記 |
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Anik Budhi, Dharmayanthi：Department of Evolutionary Studies of Biosystems, SOKENDAI (The Graduate University for Advanced Studies) |
| 著者注記 |
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Yohei, Terai：Department of Evolutionary Studies of Biosystems, SOKENDAI (The Graduate University for Advanced Studies) *(Assistant Professor） |
| 著者注記 |
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Yoko, Satta：Department of Evolutionary Studies of Biosystems, SOKENDAI (The Graduate University for Advanced Studies) *(Professor) |
| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Like Chinese Silkie, Indonesian Ayam Cemani exhibits fibromelanosis or dermal hyperpigmentation and possesses complex segmental duplications on chromosome 20 that involve the endothelin 3 gene, EDN3. A genomic region, DR1 of 127 kb, together with another region, DR2 of 171 kb, was duplicated by unequal crossing over, accompanied by inversion of one DR2. Quantitative PCR and copy number variation analyses on the Cemani genome sequence confirmed the duplication of EDN3. These genetic arrangements are identical in Cemani and Silkie, indicating a single origin of the genetic cause of Fm. The two DR1s harbor two distinct EDN3 haplotypes in a form of permanent heterozygosity, although they remain allelic in the ancestral Red Jungle Fowl population and some domesticated chicken breeds, with their allelic divergence time being as recent as 0.3 million years ago. In Cemani and Silkie breeds, artificial selection favoring the Fm phenotype has left an unambiguous record for selective sweep that extends in both directions from tandemly duplicated EDN3 loci. This highly homozygous tract is different in length between Cemani and Silkie, reflecting their distinct breeding histories. It is estimated that the Fm phenotype came into existence at least 6600-9100 years ago, prior to domestication of Cemani and Silkie, and that throughout domestication there has been intense artificial selection with strength s > 50% in each breed. |
| 書誌情報 |
PLoS ONE
en : PLoS ONE
巻 12,
号 4,
p. e0173147,
発行日 2017-04-05
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| 雑誌情報 |
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Publication Start Year : 2006 |
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Frequency : Monthly |
| 雑誌情報 |
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A Peer-Reviewed, Open Access Journal, Electronic only |
| 出版者 |
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出版者 |
Public Library of Science / San Francisco, CA |
| Online ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1932-6203 |
| PubMed番号 |
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28379963 |
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https://www.ncbi.nlm.nih.gov/pubmed/?term=28379963 |
| PMC番号 |
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PMC5381777 |
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381777/ |
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
http://dx.doi.org/10.1371/journal.pone.0173147 |
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関連名称 |
10.1371/journal.pone.0173147 ＜PLoS ONE Open Access Full Text＞ |
| 権利 |
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権利情報 |
© 2017 Dharmayanthi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | http://journals.plos.org/plosone/s/licenses-and-copyright |
| 関連サイト |
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識別子タイプ |
URI |
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関連識別子 |
https://www.ncbi.nlm.nih.gov/pmc/journals/440/ |
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関連名称 |
Archive of PLoS ONE ＜PMC Journal List＞ |
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識別子タイプ |
URI |
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関連識別子 |
http://journals.plos.org/plosone/s/journal-information |
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関連名称 |
About PLoS ONE ＜Public Library of Science＞ |
| 著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
本文 / Article (3.1 MB)
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