{"_buckets": {"deposit": "bda4d056-a33f-46e4-b3d1-f792930f7ca1"}, "_deposit": {"created_by": 1, "id": "1179", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "1179"}, "status": "published"}, "_oai": {"id": "oai:ir.soken.ac.jp:00001179", "sets": ["22"]}, "author_link": ["0", "0", "0"], "item_1_biblio_info_21": {"attribute_name": "書誌情報（ソート用）", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2006-09-29", "bibliographicIssueDateType": "Issued"}, "bibliographic_titles": [{}]}]}, "item_1_creator_2": {"attribute_name": "著者名", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "中田, 大貴"}], "nameIdentifiers": [{"nameIdentifier": "0", "nameIdentifierScheme": "WEKO"}]}]}, "item_1_creator_3": {"attribute_name": "フリガナ", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "ナカタ, ヒロキ"}], "nameIdentifiers": [{"nameIdentifier": "0", "nameIdentifierScheme": "WEKO"}]}]}, "item_1_date_granted_11": {"attribute_name": "学位授与年月日", "attribute_value_mlt": [{"subitem_dategranted": "2006-09-29"}]}, "item_1_degree_grantor_5": {"attribute_name": "学位授与機関", "attribute_value_mlt": [{"subitem_degreegrantor": [{"subitem_degreegrantor_name": "総合研究大学院大学"}]}]}, "item_1_degree_name_6": {"attribute_name": "学位名", "attribute_value_mlt": [{"subitem_degreename": "博士（理学）"}]}, "item_1_description_1": {"attribute_name": "ID", "attribute_value_mlt": [{"subitem_description": "2006528", "subitem_description_type": "Other"}]}, "item_1_description_12": {"attribute_name": "要旨", "attribute_value_mlt": [{"subitem_description": "The go/nogo task is a useful paradigm for recording event-related\u003cbr /\u003epotentials (ERPs) to investigate the neural mechanisms of response\u003cbr /\u003einhibition.  In nogo trials, a negative deflection at around 140-300 ms,\u003cbr /\u003ewhich has been called the ‘nogo potentials’ is elicited at the frontocentral \u003cbr /\u003eelectrodes, compared with ERPs recorded in go trials.  In the first study, \u003cbr /\u003ewe investigated the generators for nogo potentials by recording \u003cbr /\u003emagnetoencephalography (MEG) during somatosensory go/nogo tasks.  \u003cbr /\u003eMEG data revealed that a long-latency response peaking at approximately \u003cbr /\u003e160 ms, termed nogo-M170, recorded in only nogo trials.  The equivalent \u003cbr /\u003ecurrent dipole (ECD) of nogo-M170 was estimated to lie around the \u003cbr /\u003eposterior part of the inferior frontal sulci in the prefrontal cortex.  This \u003cbr /\u003efinding clarified the spatial and temporal processing related to \u003cbr /\u003esomato-motor inhibition caused in the posterior part of the inferior frontal \u003cbr /\u003esulci in the prefrontal cortex in humans.\u003cbr /\u003eIn the second study, we investigated the effect of the inhibitory \u003cbr /\u003eprocessing with increasing muscle force on motor evoked potentials \u003cbr /\u003e(MEPs) elicited by transcranial magnetic stimulation (TMS).  The \u003cbr /\u003esubjects performed a warning stimulus (S1) －imperative stimulus (S2) \u003cbr /\u003eparadigm with go/nogo tasks.  S1 was an auditory tone burst, and S2 was \u003cbr /\u003ean electrical stimulation for the second (go stimuli) or fifth digit (nogo \u003cbr /\u003estimuli) of the left hand at an even probability in go/nogo tasks.  The \u003cbr /\u003erecordings were conducted at three force levels; 10 %, 30 % and 50 % \u003cbr /\u003emaximal voluntary contraction (MVC).  After the presentation of S2, the \u003cbr /\u003esubjects were asked to adjust their force level so as to match the target line \u003cbr /\u003ewith a force trajectory line as quickly and accurately as possible in only the \u003cbr /\u003ego trials.  The amplitude of the MEP, which was recorded from the first \u003cbr /\u003edorsal interosseous (FDI) muscle 150 ms after S2, in nogo trials became \u003cbr /\u003esignificantly smaller with increasing muscle force, whereas it became \u003cbr /\u003elarger in go trials.  Our results indicated that stronger inhibitory cerebral \u003cbr /\u003eactivity was needed for a nogo stimulus, in the case where a stronger \u003cbr /\u003eresponse was needed for a go stimulus.", "subitem_description_type": "Other"}]}, "item_1_description_18": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_1_description_7": {"attribute_name": "学位記番号", "attribute_value_mlt": [{"subitem_description": "総研大甲第1008号", "subitem_description_type": "Other"}]}, "item_1_select_14": {"attribute_name": "所蔵", "attribute_value_mlt": [{"subitem_select_item": "有"}]}, "item_1_select_8": {"attribute_name": "研究科", "attribute_value_mlt": [{"subitem_select_item": "生命科学研究科"}]}, "item_1_select_9": {"attribute_name": "専攻", "attribute_value_mlt": [{"subitem_select_item": "20 生理科学専攻"}]}, "item_1_text_10": {"attribute_name": "学位授与年度", "attribute_value_mlt": [{"subitem_text_value": "2006"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "NAKATA, Hiroki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "0", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2016-02-17"}], "displaytype": "simple", "download_preview_message": "", "file_order": 0, "filename": "甲1008_要旨.pdf", "filesize": [{"value": "343.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 343400.0, "url": {"label": "要旨・審査要旨", "url": "https://ir.soken.ac.jp/record/1179/files/甲1008_要旨.pdf"}, "version_id": "fa09cabd-2b8b-4b8d-a47b-52d3919e2c8d"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2016-02-17"}], "displaytype": "simple", "download_preview_message": "", "file_order": 1, "filename": "甲1008_本文.pdf", "filesize": [{"value": "2.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 2200000.0, "url": {"label": "本文", "url": "https://ir.soken.ac.jp/record/1179/files/甲1008_本文.pdf"}, "version_id": "4ac96331-81ca-4d53-b856-d8f465310963"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "thesis", "resourceuri": "http://purl.org/coar/resource_type/c_46ec"}]}, "item_title": "Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm"}, {"subitem_title": "Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm", "subitem_title_language": "en"}]}, "item_type_id": "1", "owner": "1", "path": ["22"], "permalink_uri": "https://ir.soken.ac.jp/records/1179", "pubdate": {"attribute_name": "公開日", "attribute_value": "2010-02-22"}, "publish_date": "2010-02-22", "publish_status": "0", "recid": "1179", "relation": {}, "relation_version_is_last": true, "title": ["Investigation of somato-motor inhibitory processing in humans using Go/No-go paradigm"], "weko_shared_id": -1}