{"_buckets": {"deposit": "984f07fc-d334-4658-884a-da7b8375387f"}, "_deposit": {"created_by": 21, "id": "3956", "owners": [21], "pid": {"revision_id": 0, "type": "depid", "value": "3956"}, "status": "published"}, "_oai": {"id": "oai:ir.soken.ac.jp:00003956", "sets": ["293"]}, "author_link": ["2062", "368", "367", "2061", "2063"], "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2012-04", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "437", "bibliographicPageStart": "431", "bibliographicVolumeNumber": "113", "bibliographic_titles": [{"bibliographic_title": "Journal of Bioscience and Bioengineering"}, {"bibliographic_title": "Journal of Bioscience and Bioengineering", "bibliographic_titleLang": "en"}]}]}, "item_10001_creator_3": {"attribute_name": "著者別名", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "田辺, 秀之"}], "nameIdentifiers": [{"nameIdentifier": "367", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "1000050261178", "nameIdentifierScheme": "NRID", "nameIdentifierURI": " "}, {"nameIdentifier": "50261178", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=50261178"}]}]}, "item_10001_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Curved DNA structures with a left-handed superhelical conformation can activate eukaryotic transcription. Mechanistically, these structures favor binding to histone cores and can function as a docking site for sliding nucleosomes. Thus, promoters with this kind of curved DNA can adopt a more open structure, facilitating transcription initiation. However, whether the curved DNA segment can affect localization of a reporter gene is an open question. Localization of a gene in the nucleus often plays an important role in its expression and this phenomenon may also have a curved DNA-dependent mechanism. We examined this issue in transient and stable assay systems using a 180-bp synthetic curved DNA with a left-handed superhelical conformation. The results clearly showed that curved DNA of this kind does not have a property to deliver reporter constructs to nuclear positions that are preferable for transcription. We also identify the spatial location to which electroporation delivers a reporter plasmid in the nucleus.", "subitem_description_type": "Abstract"}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier"}]}, "item_10001_relation_14": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "10.1016/j.jbiosc.2011.11.022"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.1016/j.jbiosc.2011.11.022", "subitem_relation_type_select": "DOI"}}]}, "item_10001_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2011 The Society for Biotechnology, Japan."}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1389-1723", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "UDAGAWA, Koji "}], "nameIdentifiers": [{"nameIdentifier": "2061", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "KIMURA, Hajime "}], "nameIdentifiers": [{"nameIdentifier": "2062", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "TANABE, Hideyuki"}], "nameIdentifiers": [{"nameIdentifier": "368", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "OHYAMA, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "2063", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Nuclear localization of reporter genes activated by curved DNA", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Nuclear localization of reporter genes activated by curved DNA"}, {"subitem_title": "Nuclear localization of reporter genes activated by curved DNA", "subitem_title_language": "en"}]}, "item_type_id": "10001", "owner": "21", "path": ["293"], "permalink_uri": "https://ir.soken.ac.jp/records/3956", "pubdate": {"attribute_name": "公開日", "attribute_value": "2013-09-18"}, "publish_date": "2013-09-18", "publish_status": "0", "recid": "3956", "relation": {}, "relation_version_is_last": true, "title": ["Nuclear localization of reporter genes activated by curved DNA"], "weko_shared_id": 21}