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  1. 010 学術雑誌論文
  2. 田辺, 秀之 / TANABE, Hideyuki

Analysis by fluorescence in situ hybridization with a mouse gamma satellite DNA probe of isolated micronuclei induced in mice by two clastogens and two spindle poisons

https://ir.soken.ac.jp/records/3987
https://ir.soken.ac.jp/records/3987
7bc3cb21-b32d-4537-8b7e-9a4f7de40976
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-09-25
タイトル
タイトル Analysis by fluorescence in situ hybridization with a mouse gamma satellite DNA probe of isolated micronuclei induced in mice by two clastogens and two spindle poisons
タイトル
言語 en
タイトル Analysis by fluorescence in situ hybridization with a mouse gamma satellite DNA probe of isolated micronuclei induced in mice by two clastogens and two spindle poisons
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 MäKI-PAAKKANEN, Jorma

× MäKI-PAAKKANEN, Jorma

WEKO 2144

MäKI-PAAKKANEN, Jorma

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HAYASHI, Makoto

× HAYASHI, Makoto

WEKO 2108

HAYASHI, Makoto

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SUZUKI, Takayoshi

× SUZUKI, Takayoshi

WEKO 2145

SUZUKI, Takayoshi

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TANABE, Hideyuki

× TANABE, Hideyuki

WEKO 368

TANABE, Hideyuki

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HONMA, Masamitsu

× HONMA, Masamitsu

WEKO 2109

HONMA, Masamitsu

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SOFUNI, Toshio

× SOFUNI, Toshio

WEKO 2132

SOFUNI, Toshio

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著者別名 田辺, 秀之

× 田辺, 秀之

WEKO 367
NRID 1000050261178
e-Rad 50261178

田辺, 秀之

Search repository
抄録
内容記述タイプ Abstract
内容記述 The presence of centromeric DNA was studied in micronuclei isolated from the blood of male ddY mic after five weekly intraperitoneal injections of mitomycu C (MMC), 1-β-D-arabinofuranosylcytosine (Ara-C), colchi cine (COL) or vinblastine sulfate (VBL). In agreement with our earlier findings, about half of the micronuclei isolate* from vehicle control mice showed centromere signals a analyzed by fluorescence in situ hybridization (FISH) with a mouse major (gamma) satellite DNA probe. In an earlie experiment with mice acutely exposed to the same chem icals, the clastogens MMC and Ara-C did not reduce thi proportion of micronuclei with centromere signals. In the present study, however, MMC and Ara-C decreased the proportion of micronuclei with centromeres. In contrast the spindle poisons COL and VBL increased the proportion of micronuclei that contained centromeres.
書誌情報 Mutagenesis
en : Mutagenesis

巻 10, 号 6, p. 513-516, 発行日 1995-11
出版者
出版者 Oxford University Press
ISSN
収録物識別子タイプ ISSN
収録物識別子 0267-8357
DOI
識別子タイプ DOI
関連識別子 https://doi.org/10.1093/mutage/10.6.513
関連名称 10.1093/mutage/10.6.513
権利
権利情報 © Oxford University Press
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